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03.2150.400

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Utilizing ENU mutagenesis. we identified a mutant mouse with elevated platelets. Genetic mapping localized the mutation to an interval on chromosome 19 that encodes the Jak2 tyrosine kinase. We identified a A3056T mutation resulting in a premature stop codon within exon 19 of Jak2 (Jak2(K915X)). https://www.spidertattooz.com/Zenith-El-Primero-36-000-VpH-03-2150-400/
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