Abstract Background Oncogenesis rewires signaling networks to confer a fitness advantage to malignant cells. For instance. the B16F0 melanoma cell model creates a cytokine sink for Interleukin-12 (IL-12) to deprive neighboring cells of this important anti-tumor immune signal. While a cytokine sink provides an indirect fitness advantage. https://trendingcustomes.shop/product-category/7-5-x-4-5/